Tackle IBD
with microfluidics
OUR MOTIVATION
Spasmodic, sudden course
Inflammatory bowel diseases (short: IBD) are long-term conditions associated with inflammations in the gastrointestinal tract.
Although the principal types of IBD, Crohns´s disease and ulcerative colitis, effect different parts of the gastrointestinal tract, they have some things in common: Both are incurable and restrain the daily life of patients.
Diarrhoea
Fever
Performance problems
Fatigue
Lack of concentration
PATIENTS
300.000
More than 300.000 people in Germany alone and many more worldwide are suffering from IBDs on a daily basis. We would like to help these people.
4000
NEW CASES
Germany alone, has an increasing number of cases. Every year, an average of 4000 new cases add up and the incidence rate is continuously increasing.
15-45
YEARS OLD
The majority of patients are between 15 and 45 years old. Therefore, most people with an IBD suffer from symptoms very early on in life and need permanent medical treatment.
Patients with inflammatory bowel diseases often suffer from restraints to their daily life.
We want to help them to control their disease on their own and consequently enjoy a liberated life without any restraints.
OUR PROJECT
THE CHALLENGE
Patients with inflammatory bowel diseases are severely limited in their everyday lives and can only rely on the monitoring by their doctors in order to keep track of disease progress.
Therefore, we would like to bring the monitoring to the patients home. This allows them to monitor independently without having to visit the doctor's office.
We want to generate fast, quantitative and precise results to alert the patient to possible exacerbations.
Additionally, the system should be low-cost and affordable for every patient.
THE VISION
-
Sample filtration and dilution
-
Sample application on a microfluidic chip
-
biological reaction on the chip by lateral flow assay
-
evaluation via portable analyzer
-
quantitative result
THE TECHNOLOGY
-
handy chip size
-
Cheap and easy to process polymer material
-
No active parts, due to capillary effect
-
on Chip antibody-antigen reaction
-
fluorescence based detection
OUR TEAM
Maschinenbau, KIT
Medizintechnik
Mikrosystemtechnik
This is a great place to tell your story and give people more insight into who you are, what you do, and why it’s all about you.
Karlsruhe Insitute of Technology
medical & micro-
systems engineering
"We are aiming to develop product that could help patients managing their inflammatory bowel disease "
Karlsruhe Insitute of Technology
medical engineering
& polymer engineering
"In the long run, I hope our idea will make life easier for many IBD-patients."
University of Freiburg
Biochemistry
& Biophysics
"I want to use the skills I learned during my studies to develop a technology that improves the lives of chronically ill."
Karlsruhe Institute of Technology
medical engineering
& robotics
"Furthermore we want to raise awareness for chronic inflammatory bowel disease."